Since 2009, ASPI has sought to strengthen relations between Myanmar and the outside world and support Myanmar’s economic and political development. ASPI’s initial work produced policy recommendations for the U.S. to advance Myanmar's reform process in a phased process. ASPI also worked to convene informal dialogues among experts and former policymakers from the U.S. and Myanmar, with the aim of strengthening bilateral relations and supporting Myanmar’s democratic transition.

Today, through analysis and recommendations papers, public events, strategic dialogues, and expert commentary, ASPI continues to support the strengthening of Myanmar’s economic development and democratic institutions, as well as advocate for increased engagement with the United States and multilateral institutions. ASPI has published multiple reports for policymakers and hosted seminal discussions with Myanmar’s leaders including then President Thein Sein and State Counsellor Aung San Suu Kyi.